Vladimír Havlíček

Vladimír Havlíček earned his Ph.D. in analytical chemistry specializing in organic technology at the Prague Institute of Chemical Technology. Following a postdoctoral fellowship at the University of Washington in Seattle, he commenced research in proteomics, lipidomics, and metabolomics utilizing mass spectrometry imaging and ambient ionization techniques in the Czech Republic. Since 2006, he has held the position of Chair at the Laboratory of Molecular Structure Characterization located at the Institute of Microbiology in Prague, Czech Republic. The laboratory is currently equipped with microbiology, mass spectrometry, nuclear magnetic resonance, and electron microscopy instruments. During a four-month sabbatical in 2022, he received training in infection microbiology and analytical chemistry from K.A. Schug at UTA in Texas and D.A. Stevens at CIMR in California. In the field of medicine, the laboratory team offers instrumental assistance to research groups located both on campus and abroad. Their research focuses on non-communicable as well as infectious diseases. The laboratory's core analytical concept, infection metallomics, examines how antimicrobial therapies impact host-microbial consortia interactions in infections located in the lung, central nervous system, and urogenital tract.

Abstract Submission:

The identification of the developmental stage of infection in critically ill patients can be achieved through the analysis of Aspergillus secondary metabolites (mycotoxins and fungal siderophores) and host pentraxin-3 profiles. Characteristic traits obtained from in vitro and animal experiments, which feature time-resolved events of molecular secretion, have been transposed to human diagnostics.