Dr. Ibrahim’s research focuses on molecular pathogenesis, host-pathogen interactions, immunotherapies, and models of infections to advance the understanding of the pathogenic mechanisms and virulence factors of fungal and bacterial infections and translate this knowledge into novel therapeutic strategies. His research is focused on the following areas: 1) The host-pathogen interactions in mucormycosis and the development of rapid diagnostics and novel antibody-based therapy; 2) Unnatural immunity for the development of vaccine strategies that target multidrug resistant organisms including MDR Candida species, and Gram-negative bacteria; 3) Mechanisms of microbial sepsis for development of novel immunotherapies; and 4) Antifungal drug discovery.